Deletion of Dtnbp1 in mice impairs threat memory consolidation and is associated with enhanced inhibitory drive in the amygdala

Schizophrenia is a severe and highly heritable disorder. Dystrobrevin-binding protein 1 ( DTNBP1 ), also known as dysbindin-1, has been implicated in the pathophysiology of schizophrenia. Specifically, dysbindin-1 mRNA and protein expression are decreased in the brains of subjects with this disorder...

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