Dissection of Complex, Fitness-Related Traits in Multiple Drosophila Mapping Populations Offers Insight into the Genetic Control of Stress Resistance

We leverage two complementary mapping panels to genetically dissect starvation resistance-an important fitness trait. Using >1600 genotypes from the multiparental Synthetic Population Resource (DSPR), we map numerous starvation stress QTL that collectively explain a substantial fraction of trait...

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Veröffentlicht in:	Genetics (Austin) 2019-04, Vol.211 (4), p.1449-1467
Hauptverfasser:	Everman, Elizabeth R, McNeil, Casey L, Hackett, Jennifer L, Bain, Clint L, Macdonald, Stuart J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Correlation analysis Desiccation Drosophila Drosophila melanogaster Drying Evolution Fitness Gene expression Gene mapping Genetic control Genetic Fitness Genetics Genome, Insect Genome-Wide Association Study - methods Genome-Wide Association Study - standards Genotypes Heritability Insects Investigations Lipids Mapping Metabolism Multifactorial Inheritance Phenotypes Polygenic inheritance Quantitative Trait Loci Quantitative Trait, Heritable Reproductive fitness Starvation - genetics Stress, Physiological - genetics
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