The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study

Abstract Given clear evidence that smoking lowers weight, it is possible that individuals with higher body mass index (BMI) smoke in order to lose or maintain their weight. We performed Mendelian randomization (MR) analyses of the effects of BMI on smoking behaviour in UK Biobank and the Tobacco and...

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Veröffentlicht in:	Human molecular genetics 2019-04, Vol.28 (8), p.1322-1330
Hauptverfasser:	Taylor, Amy E, Richmond, Rebecca C, Palviainen, Teemu, Loukola, Anu, Wootton, Robyn E, Kaprio, Jaakko, Relton, Caroline L, Davey Smith, George, Munafò, Marcus R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Body Mass Index Body Weight - genetics Cohort Studies DNA Methylation - genetics Female Genome-Wide Association Study - methods Humans Longitudinal Studies Male Mendelian Randomization Analysis - methods Middle Aged Nicotine - genetics Nicotine - metabolism Polymorphism, Single Nucleotide - genetics Risk Factors Smoking - genetics Smoking - metabolism Smoking - physiopathology Smoking Cessation
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