A Simple Competing Endogenous RNA Network Identifies Novel mRNA, miRNA, and lncRNA Markers in Human Cholangiocarcinoma

Background. Cholangiocarcinoma (CCA) is the second most common malignant primary liver tumor and has shown an alarming increase in incidence over the last two decades. However, the mechanisms behind tumorigenesis and progression remain insufficient. The present study aimed to uncover the underlying...

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Veröffentlicht in:	BioMed research international 2019-01, Vol.2019 (2019), p.1-13
Hauptverfasser:	Zhang, Cheng, Ge, Chunlin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Bile Duct Neoplasms - genetics Bile Duct Neoplasms - metabolism Bile Duct Neoplasms - pathology Bioinformatics Biomarkers Cancer Cholangiocarcinoma Cholangiocarcinoma - genetics Cholangiocarcinoma - metabolism Cholangiocarcinoma - mortality Colorectal cancer Competition Development and progression Disease-Free Survival Female Gene sequencing Genetic aspects Genomes Genomics Humans Kidney cancer Liver Liver cancer Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - mortality Male Medical prognosis Messenger RNA MicroRNA MicroRNAs - biosynthesis MicroRNAs - genetics Middle Aged miRNA Mortality mRNA Oncology Patients Proteins Regulatory mechanisms (biology) Ribonucleic acid RNA RNA, Long Noncoding - biosynthesis RNA, Long Noncoding - genetics RNA, Messenger - biosynthesis RNA, Messenger - genetics RNA, Neoplasm - biosynthesis RNA, Neoplasm - genetics Sequence Analysis, RNA Survival analysis Survival Rate Tumorigenesis
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