High resolution discovery of chromatin interactions

Abstract Chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) is a method for the genome-wide de novo discovery of chromatin interactions. Existing computational methods typically fail to detect weak or dynamic interactions because they use a peak-calling step that ignores paired-e...

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Veröffentlicht in:	Nucleic acids research 2019-04, Vol.47 (6), p.e35-e35
Hauptverfasser:	Guo, Yuchun, Krismer, Konstantin, Closser, Michael, Wichterle, Hynek, Gifford, David K
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Chromatin - chemistry Chromatin - metabolism Chromatin Immunoprecipitation - methods Computational Biology - methods Datasets as Topic DNA-Binding Proteins - analysis DNA-Binding Proteins - metabolism Expressed Sequence Tags Humans Methods Online Protein Binding Sequence Analysis, DNA - methods
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