Breast Cancer Cells Adapt Contractile Forces to Overcome Steric Hindrance

Cell migration through the extracellular matrix is governed by the interplay between cell-generated propulsion forces, adhesion forces, and resisting forces arising from the steric hindrance of the matrix. Steric hindrance in turn depends on matrix porosity, matrix deformability, cell size, and cell...

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Veröffentlicht in:	Biophysical journal 2019-04, Vol.116 (7), p.1305-1312
Hauptverfasser:	Cóndor, Mar, Mark, Christoph, Gerum, Richard C., Grummel, Nadine C., Bauer, Andreas, García-Aznar, José M., Fabry, Ben
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Cell Line, Tumor Cell Movement Cell Shape Collagen - chemistry Epithelial Cells - physiology Extracellular Matrix - chemistry Humans Lamin Type A - metabolism Stress, Mechanical
Online-Zugang:	Volltext
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