Health-Related Quality of Life and Emotional Health in X-Linked Carriers of Chronic Granulomatous Disease in the United Kingdom

X-linked chronic granulomatous disease (XL-CGD), a rare primary immunodeficiency due to a defect in the gp91 phox NADPH oxidase subunit, results in recurrent, severe infection, inflammation, and autoimmunity. Patients have an absent, or significantly reduced, neutrophil oxidative burst. Due to lyoni...

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Veröffentlicht in:	Journal of clinical immunology 2019-02, Vol.39 (2), p.195-199
Hauptverfasser:	Battersby, Alexandra C., Braggins, Helen, Pearce, Mark S., McKendrick, Fiona, Campbell, Mari, Burns, Siobhan, Cale, Catherine M., Goldblatt, David, Gennery, Andrew R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anxiety Anxiety - genetics Anxiety - psychology Autoimmunity Biomedical and Life Sciences Biomedicine Child Child, Preschool Chronic granulomatous disease Depression - genetics Depression - psychology Fatigue Female Genes, X-Linked Granulomatous Disease, Chronic - genetics Granulomatous Disease, Chronic - psychology Humans Immunodeficiency Immunology Infectious Diseases Internal Medicine Intestine Medical Microbiology Mental depression Mental Health Middle Aged NAD(P)H oxidase Original Original Article Phagocytes Primary immunodeficiencies Quality of Life Questionnaires Recurrent infection United Kingdom Young Adult
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