Use of Targeted Next-Generation Sequencing to Identify Activating Hot Spot Mutations in Cherry Angiomas

IMPORTANCE: Shared gene variants in benign-malignant process pairs, such as BRAF mutations common to benign nevi and melanoma, are associated with differing phenotypic manifestations. Study of gene mechanisms underlying cherry angioma may uncover previously unknown disease relationships. OBJECTIVE:...

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Veröffentlicht in:	Archives of dermatology (1960) 2019-02, Vol.155 (2), p.211-215
Hauptverfasser:	Klebanov, Nikolai, Lin, William M, Artomov, Mykyta, Shaughnessy, Michael, Njauw, Ching-Ni, Bloom, Romi, Eterovic, Agda Karina, Chen, Ken, Kim, Tae-Beom, Tsao, Sandy S, Tsao, Hensin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Boston Brief Report Clinical outcomes Female Gene expression Genetic Predisposition to Disease - epidemiology Genotype & phenotype GTP-Binding Protein alpha Subunits, Gq-G11 - genetics Hemangioma - genetics Hemangioma - pathology High-Throughput Nucleotide Sequencing - methods Humans Incidence Male Melanoma Middle Aged Mutation Mutation, Missense Online First Risk Assessment Sampling Studies Sex Factors Skin Neoplasms - genetics Skin Neoplasms - pathology Tissue Embedding
Online-Zugang:	Volltext
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