Association of Combined Naltrexone and Ketamine With Depressive Symptoms in a Case series of Patients With Depression and Alcohol Use Disorder

This study examines whether naltrexone pretreatment interferes with the antidepressant effects of ketamine.

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Bibliographische Detailangaben
Veröffentlicht in:	JAMA psychiatry (Chicago, Ill.) Ill.), 2019-03, Vol.76 (3), p.337-338
Hauptverfasser:	Yoon, Gihyun, Petrakis, Ismene L, Krystal, John H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alcohol Drinking - drug therapy Alcohol use Alcoholism - complications Alcoholism - drug therapy Craving - drug effects Depressive Disorder, Major - complications Depressive Disorder, Major - drug therapy Drug Therapy, Combination Female Humans Ketamine Ketamine - adverse effects Ketamine - therapeutic use Letters Male Mental depression Middle Aged Naltrexone - adverse effects Naltrexone - therapeutic use Online First Patients Pilot Projects Prescription drugs Research Letter
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Beschreibung
Zusammenfassung:	This study examines whether naltrexone pretreatment interferes with the antidepressant effects of ketamine.
ISSN:	2168-622X 2168-6238
DOI:	10.1001/jamapsychiatry.2018.3990