Assessment of Racial Disparities in Biomarkers for Alzheimer Disease

IMPORTANCE: Racial differences in molecular biomarkers for Alzheimer disease may suggest race-dependent biological mechanisms. OBJECTIVE: To ascertain whether there are racial disparities in molecular biomarkers for Alzheimer disease. DESIGN, SETTING, AND PARTICIPANTS: A total of 1255 participants (...

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Veröffentlicht in:	Archives of neurology (Chicago) 2019-03, Vol.76 (3), p.264-273
Hauptverfasser:	Morris, John C, Schindler, Suzanne E, McCue, Lena M, Moulder, Krista L, Benzinger, Tammie L. S, Cruchaga, Carlos, Fagan, Anne M, Grant, Elizabeth, Gordon, Brian A, Holtzman, David M, Xiong, Chengjie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult African Americans Alzheimer Disease - cerebrospinal fluid Alzheimer Disease - diagnosis Alzheimer's disease Amyloid beta-Peptides - cerebrospinal fluid Analysis of covariance Apolipoprotein E Apolipoprotein E4 - cerebrospinal fluid Biomarkers Biomarkers - cerebrospinal fluid Brain Cerebrospinal fluid Cognition Colleges & universities Correlation analysis Cortex Covariance Cross-Sectional Studies Dementia Dementia disorders Emission analysis Female Genetics Hippocampus Humans Ischemia Lesions Longitudinal studies Magnetic resonance imaging Male Medical imaging Men Middle Aged Minority & ethnic groups Neurodegenerative diseases Neuroimaging NMR Nuclear magnetic resonance Online First Original Investigation Peptide Fragments - cerebrospinal fluid Positron emission Positron emission tomography Race Resonance Tau protein tau Proteins - cerebrospinal fluid Variance analysis
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