Dose Selection and Validation for Ceftazidime-Avibactam in Adults with Complicated Intra-abdominal Infections, Complicated Urinary Tract Infections, and Nosocomial Pneumonia

Avibactam is a non-β-lactam β-lactamase inhibitor that has been approved in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and nosocomial pneumonia, including ventilator-associated pneumonia. In Europe, ceftazidime-avib...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2019-04, Vol.63 (4)
Hauptverfasser:	Das, Shampa, Li, Jianguo, Riccobene, Todd, Carrothers, Timothy J, Newell, Paul, Melnick, David, Critchley, Ian A, Stone, Gregory G, Nichols, Wright W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacokinetics Azabicyclo Compounds Azabicyclo Compounds - administration & dosage Azabicyclo Compounds - pharmacokinetics Ceftazidime Ceftazidime - administration & dosage Ceftazidime - pharmacokinetics Drug Combinations Healthcare-Associated Pneumonia Healthcare-Associated Pneumonia - drug therapy Healthcare-Associated Pneumonia - microbiology Humans Intraabdominal Infections Intraabdominal Infections - drug therapy Intraabdominal Infections - microbiology Microbial Sensitivity Tests - methods Minireview Urinary Tract Infections Urinary Tract Infections - drug therapy Urinary Tract Infections - microbiology
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