Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

ABSTRACTCone photoreceptors are essential for vision under moderate to high illuminance and allow color discrimination. Their fast dark adaptation rate and resistance to saturation are believed to depend in part on an intraretinal visual cycle that supplies 11‐cis‐retinaldehyde to cone opsins. Candi...

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Veröffentlicht in:	The FASEB journal 2019-04, Vol.33 (4), p.5782-5792
Hauptverfasser:	Kiser, Philip D., Kolesnikov, Alexander V., Kiser, Jianying Z., Dong, Zhiqian, Chaurasia, Bhagirath, Wang, Liping, Summers, Scott A., Hoang, Thanh, Blackshaw, Seth, Peachey, Neal S., Kefalov, Vladimir J., Palczewski, And Krzysztof
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Degs1 Ependymoglial Cells - metabolism Male Membrane Proteins - metabolism Mice Mice, Knockout Müller glia Oxidoreductases - metabolism photoreceptor Receptor, Platelet-Derived Growth Factor alpha - metabolism Retina - metabolism Retinal Cone Photoreceptor Cells - metabolism Retinal Pigment Epithelium - metabolism Retinal Rod Photoreceptor Cells - metabolism Retinaldehyde - metabolism retinoid cycle sphingolipidδ desaturase Transducin - metabolism Vision, Ocular - physiology
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