Cancer immunology and radiobiology: Oliver Scott's struggle for the perfect tumour model in translational research
Oliver Scott is best known for his research into the role of tumour hypoxia in radiation oncology. Yet no less important were Oliver's activities in the development of concepts and methods for performing translational research on the effect of ionising radiation on tumour in experimental animal...
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| Veröffentlicht in: | British journal of radiology 2019, Vol.92 (1093), p.20180188-20180188 |
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| container_title | British journal of radiology |
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| creator | Trott, Klaus-Rüdiger |
| description | Oliver Scott is best known for his research into the role of tumour hypoxia in radiation oncology. Yet no less important were Oliver's activities in the development of concepts and methods for performing translational research on the effect of ionising radiation on tumour in experimental animals, stressing the importance of using strictly inbred animals for transplantation of tumours which had arisen in exactly the identical mouse strain. Otherwise residual immunity would lead to uncontrollable bias in the results of cure experiments, invalidating conclusions. These pioneering views are no less valid in today's cancer research. |
| doi_str_mv | 10.1259/bjr.20180188 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0007-1285 |
| ispartof | British journal of radiology, 2019, Vol.92 (1093), p.20180188-20180188 |
| issn | 0007-1285 1748-880X |
| language | eng |
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| source | MEDLINE; Oxford University Press; EZB Electronic Journals Library |
| subjects | Animals History, 20th Century Humans Immunotherapy - history Immunotherapy - methods Mice Neoplasms, Experimental - immunology Neoplasms, Experimental - therapy Pushing the frontiers of radiobiology: A special feature in memory of Sir Oliver Scott and Professor Jack Fowler Radiobiology - history Scott Translational Medical Research - history |
| title | Cancer immunology and radiobiology: Oliver Scott's struggle for the perfect tumour model in translational research |
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