Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities

Mesenchymal stromal cells (MSCs) have been the subject of clinical trials for more than a generation, and the outcomes of advanced clinical trials have fallen short of expectations raised by encouraging pre-clinical animal data in a wide array of disease models. In this Perspective, important biolog...

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Veröffentlicht in:	Cell stem cell 2018-06, Vol.22 (6), p.824-833
Hauptverfasser:	Galipeau, Jacques, Sensébé, Luc
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals biomarkers clinical trials Crohn’s disease efferocytosis FDA graft versus host disease Graft vs Host Disease - therapy Humans immune compatibility Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism mesenchymal stromal cells thawing
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