MicroRNA‐488 inhibits endometrial glandular epithelial cell proliferation, migration, and invasion in endometriosis mice via Wnt by inhibiting FZD7

Endometriosis is a chronic inflammatory syndrome and nearly 6%‐10% of women are affected by it during the reproductive period. Previous studies have proved that microRNAs (miRNAs) are implicated in the pathogenesis of ovarian endometriosis. In this study, we aimed to investigate that restored miR‐48...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2019-04, Vol.23 (4), p.2419-2430
Hauptverfasser:	Zhu, Hui, Cao, Xi‐Xia, Liu, Juan, Hua, Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Activation Animals Antibodies Apoptosis Binding sites Cancer Catenin Cell activation Cell adhesion & migration Cell cycle Cell growth Cell migration Cell Movement - genetics Cell proliferation Cell Proliferation - genetics Cloning Data processing Disease Models, Animal DNA microarrays endometrial glandular epithelial cells Endometriosis Endometriosis - genetics Endometriosis - pathology Endometrium Endometrium - metabolism Endometrium - pathology Epithelial cells Epithelial Cells - metabolism Epithelial Cells - pathology Ethanol Female Frizzled protein Frizzled Receptors - genetics FZD7 Gene expression Gene Expression Regulation, Neoplastic Humans Inflammation Kinases Laboratory animals Mice MicroRNAs MicroRNAs - genetics microRNA‐488 Migration miRNA Myc protein Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Nuclei (cytology) Original Pyruvic acid Tissues Translocation Uterus Wnt protein Wnt Signaling Pathway - genetics Wnt signalling pathway
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