Nickel-catalyzed oxidative C-H/N-H annulation of N -heteroaromatic compounds with alkynes

The reaction of N-heteroaromatic compounds, such as 2-aryl-pyrrole, benzimidazole, imidazole, indole, and pyrazole derivatives, with alkynes in the presence of a catalytic amount of a nickel complex results in C-H/N-H oxidative annulation. The reaction shows a high functional group compatibility. Wh...

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Veröffentlicht in:Chemical science (Cambridge) 2019-03, Vol.10 (11), p.3242-3248
Hauptverfasser: Obata, Atsushi, Sasagawa, Akane, Yamazaki, Ken, Ano, Yusuke, Chatani, Naoto
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Sprache:eng
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