Proteolysis by MMP20 Prevents Aberrant Mineralization in Secretory Enamel

The present study was conducted to investigate the role of proteolysis by matrix metalloproteinase 20 (MMP20) in regulating the initial formation of the enamel mineral structure during the secretory stage of amelogenesis, utilizing Mmp20-null mice that lack this essential protease. Ultrathin sagitta...

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Veröffentlicht in:	Journal of dental research 2019-04, Vol.98 (4), p.468-475
Hauptverfasser:	Yamazaki, H., Tran, B., Beniash, E., Kwak, S.Y., Margolis, H.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ameloblasts Amelogenesis Amelogenin Animals Apatite Calcium phosphates Cell adhesion & migration Crystals Data analysis Dental enamel Dental Enamel Proteins Dentistry Electron diffraction Enamel Genotypes Incisors Laboratory animals Matrix metalloproteinase Matrix Metalloproteinase 20 Metalloproteinase Mice Mineralization Octacalcium phosphate Proteolysis Research Reports Roles Scanning electron microscopy Studies Transmission electron microscopy
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