Controversies in drug allergy: Testing for delayed reactions

Controversies exist with regard to in vivo approaches to delayed immunologically mediated adverse drug reactions, such as exanthem (maculopapular eruption), drug reaction with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome/toxic epidermal nec...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2019-01, Vol.143 (1), p.66-73
Hauptverfasser:	Phillips, Elizabeth J., Bigliardi, Paul, Bircher, Andreas J., Broyles, Ana, Chang, Yoon-Seok, Chung, Wen-Hung, Lehloenya, Rannakoe, Mockenhaupt, Maja, Peter, Jonny, Pirmohamed, Munir, Roujeau, Jean-Claude, Shear, Neil H., Tanno, Luciana Kase, Trubiano, Jason, Valluzzi, Rocco, Barbaud, Annick
Format:	Artikel
Sprache:	eng
Schlagworte:	Abacavir acute generalized exanthematous pustulosis Allergies Allergology Animals Asian People Blood diseases Carbamazepine Carbamazepine - adverse effects Carbamazepine - therapeutic use Cross-reactivity Delayed Dermatology Dideoxynucleosides - adverse effects Dideoxynucleosides - therapeutic use Drug dosages drug reaction with eosinophilia and systemic symptoms Drug tolerance Eosinophilia Eruptions fixed drug eruption Histocompatibility antigen HLA HLA HLA-B Antigens - genetics HLA-B Antigens - immunology HLA-B15 Antigen - genetics HLA-B15 Antigen - immunology Human health and pathology Humans Hypersensitivity Hypersensitivity (delayed) Immunological tolerance Immunology Immunopathogenesis intradermal Life Sciences Lymphocytes Lymphocytes T oral challenge patch Pharmaceutical sciences Phenotypes prick Pustulosis Side effects Skin diseases Skin eruptions Skin tests Skin Tests - standards Stevens-Johnson syndrome Stevens-Johnson Syndrome - genetics Stevens-Johnson Syndrome - immunology Stevens-Johnson Syndrome - pathology Stevens-Johnson syndrome/toxic epidermal necrolysis Toxic epidermal necrolysis
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