Surfactant Copolymer Annealing of Chemically Permeabilized Cell Membranes

Structural breakdown of the cell membrane is a primary mediator in trauma-induced tissue necrosis. When membrane disruption exceeds intrinsic membrane sealing processes, biocompatible multi-block amphiphilic copolymer surfactants such as Poloxamer 188 (P188) have been found to be effective in cataly...

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Veröffentlicht in:	Regenerative engineering and translational medicine 2018-03, Vol.4 (1), p.1-10
Hauptverfasser:	Chen, Hongfeng, McFaul, Colin, Titushkin, Igor, Cho, Michael, Lee, Raphael
Format:	Artikel
Sprache:	eng
Schlagworte:	Atomic force microscopes Atomic force microscopy Atomic structure Biocompatibility Biomaterials Biomedical Engineering and Bioengineering Block copolymers Cell membranes Change detection Chemistry and Materials Science Design optimization Fibroblasts Image analysis Indentation Materials Science Membranes Polyethylene glycol Regenerative Medicine/Tissue Engineering Roughness Sealing Surfactants Topography
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