Localization of Secretory Mucins MUC5AC and MUC5B in Normal/Healthy Human Airways

MUC5AC and MUC5B are the predominant gel-forming mucins in the mucus layer of human airways. Each mucin has distinct functions and site-specific expression. However, the regional distribution of expression and cell types that secrete each mucin in normal/healthy human airways are not fully understoo...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2019-03, Vol.199 (6), p.715-727
Hauptverfasser:	Okuda, Kenichi, Chen, Gang, Subramani, Durai B, Wolf, Monroe, Gilmore, Rodney C, Kato, Takafumi, Radicioni, Giorgia, Kesimer, Mehmet, Chua, Michael, Dang, Hong, Livraghi-Butrico, Alessandra, Ehre, Camille, Doerschuk, Claire M, Randell, Scott H, Matsui, Hirotoshi, Nagase, Takahide, O'Neal, Wanda K, Boucher, Richard C
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture Humans Hybridization Localization Lung - diagnostic imaging Lung - physiology Lung diseases Lungs Morphology Mucin 5AC - analysis Mucin-5B - analysis Mucous membrane Original Protein Transport - physiology Proteins Respiratory Physiological Phenomena Stem cells Transcription factors
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