Promoting remyelination through cell transplantation therapies in a model of viral‐induced neurodegenerative disease

Multiple sclerosis (MS) is a central nervous system (CNS) disease characterized by chronic neuroinflammation, demyelination, and axonal damage. Infiltration of activated lymphocytes and myeloid cells are thought to be primarily responsible for white matter damage and axonopathy. Several United State...

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Veröffentlicht in:	Developmental dynamics 2019-01, Vol.248 (1), p.43-52
Hauptverfasser:	Mangale, Vrushali, McIntyre, Laura L., Walsh, Craig M., Loring, Jeanne F., Lane, Thomas E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells (biology) Central nervous system Demyelination Derivatives Disease Models, Animal Hepatitis Humans Infiltration Inflammation Lymphocytes Mice Multiple sclerosis Multiple Sclerosis - therapy Murine hepatitis virus Myelination Myeloid cells neural precursor cells Neural stem cells Neurodegenerative Diseases - pathology Neurodegenerative Diseases - therapy Neurodegenerative Diseases - virology Progenitor cells Remyelination Stem cell transplantation Stem Cell Transplantation - methods Stem cells Substantia alba Transplantation virus Viruses
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