Translational inhibition of α-synuclein by Posiphen normalizes distal colon motility in transgenic Parkinson mice

Parkinson disease (PD) is a neurodegenerative disease with motor as well as non-motor symptoms, including gastrointestinal dysfunction. In humans, these precede the motor symptoms by decades. Previously developed and characterized transgenic mice expressing the mutant human α-synuclein gene ( ) (eit...

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Veröffentlicht in:American journal of neurodegenerative disease 2019, Vol.8 (1), p.1-15
Hauptverfasser: Kuo, Yien-Ming, Nwankwo, Ejike Innocent, Nussbaum, Robert L, Rogers, Jack, Maccecchini, Maria L
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Sprache:eng
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