PD-L1 expression combined with microsatellite instability/CD8+ tumor infiltrating lymphocytes as a useful prognostic biomarker in gastric cancer

While the importance of programmed death-ligand 1 (PD-L1), mutation burden caused by microsatellite instability (MSI), and CD8+ tumor infiltrating lymphocytes (TILs) has become evident, the significance of PD-L1 expression on prognosis still remains controversial. We evaluated the usefulness of comb...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2019-03, Vol.9 (1), p.4633-4633, Article 4633
Hauptverfasser:	Morihiro, Toshiaki, Kuroda, Shinji, Kanaya, Nobuhiko, Kakiuchi, Yoshihiko, Kubota, Tetsushi, Aoyama, Katsuyuki, Tanaka, Takehiro, Kikuchi, Satoru, Nagasaka, Takeshi, Nishizaki, Masahiko, Kagawa, Shunsuke, Tazawa, Hiroshi, Fujiwara, Toshiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1504/1829 631/67/580 82/51 Adult Aged Aged, 80 and over Apoptosis B7-H1 Antigen - genetics B7-H1 Antigen - metabolism Biomarkers Biomarkers, Tumor - blood CD8 antigen CD8-Positive T-Lymphocytes - immunology Disease-Free Survival Female Gastric cancer Humanities and Social Sciences Humans Immune status Invasiveness Kaplan-Meier Estimate Lymph nodes Lymphatic Metastasis - pathology Lymphocytes Lymphocytes, Tumor-Infiltrating - immunology Male Metastases Microsatellite Instability Microsatellite Repeats - genetics Middle Aged multidisciplinary Multivariate analysis PD-L1 protein Prognosis Proportional Hazards Models Retrospective Studies Science Science (multidisciplinary) Stomach Neoplasms - genetics Stomach Neoplasms - immunology Tumor cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!