Hydroxypropyltrimethyl Ammonium Chloride Chitosan Functionalized-PLGA Electrospun Fibrous Membranes as Antibacterial Wound Dressing: In Vitro and In Vivo Evaluation

A novel poly(lactic- -glycolic acid) (PLGA)-hydroxypropyltrimethyl ammonium chloride chitosan (HACC) composite nanofiber wound dressing was prepared through electrospinning and the entrapment-graft technique as an antibacterial dressing for cutaneous wound healing. HACC with 30% degrees of substitut...

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Veröffentlicht in:	Polymers 2017-12, Vol.9 (12), p.697
Hauptverfasser:	Yang, Shengbing, Han, Xiuguo, Jia, Yuhang, Zhang, Hongbo, Tang, Tingting
Format:	Artikel
Sprache:	eng
Schlagworte:	Atomic force microscopy Bacteria Biocompatibility Biological properties Chitosan Electron microscopy Entrapment Fibroblasts Fourier transforms Glycolic acid Immobilization Infrared analysis Membranes Mice Microscopy Nanofibers Substitution reactions Thermogravimetric analysis Toxicity Wound healing
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