TRAIP is a master regulator of DNA interstrand cross-link repair

Cells often utilize multiple pathways to repair the same DNA lesion, and pathway choice has profound implications for the fidelity of genome maintenance. DNA interstrand cross-links (ICLs) block DNA replication and transcription by covalently linking the two strands of DNA, and the cytotoxicity of I...

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Veröffentlicht in:	Nature (London) 2019-03, Vol.567 (7747), p.267-272
Hauptverfasser:	Wu, R. Alex, Semlow, Daniel R., Kamimae-Lanning, Ashley N., Kochenova, Olga V., Chistol, Gheorghe, Hodskinson, Michael R., Amunugama, Ravindra, Sparks, Justin L., Wang, Meng, Deng, Lin, Mimoso, Claudia A., Low, Emily, Patel, Ketan J., Walter, Johannes C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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