Exosomes from miRNA-126-modified ADSCs promotes functional recovery after stroke in rats by improving neurogenesis and suppressing microglia activation

Although adipose derived stem cells (ADSCs) exert their therapeutic potential in ischemic stroke, the migration of ADSCs in injured area is not apparently observed after intravenous administration. ADSCs are an important source of exosomes which hold great promise as an endogenous drug delivery syst...

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Veröffentlicht in:American journal of translational research 2019-01, Vol.11 (2), p.780-792
Hauptverfasser: Geng, Wujun, Tang, Hongli, Luo, Shan, Lv, Ya, Liang, Dongdong, Kang, Xianhui, Hong, Wandong
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Sprache:eng
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