Analysis of gene co‑expression network reveals prognostic significance of CNFN in patients with head and neck cancer

In patients with head and neck cancer (HNC), lymph node (N) metastases are associated with cancer aggressiveness and poor prognosis. Identifying meaningful gene modules and representative biomarkers relevant to the N stage helps predict prognosis and reveal mechanisms underlying tumor progression. T...

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Veröffentlicht in:	Oncology reports 2019-04, Vol.41 (4), p.2168-2180
Hauptverfasser:	Liu, Baoling, Huang, Guanhong, Zhu, Hongming, Ma, Zhaoming, Tian, Xiaokang, Yin, Li, Gao, Xingya, He, Xia
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Bioinformatics Biological markers Biomarkers, Tumor - metabolism Cancer Cancer genetics Cancer metastasis Care and treatment Chromosomes Computational Biology Criminal investigation Data collection Datasets Datasets as Topic Desmoglein 1 - metabolism Development and progression Estrogens Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Regulatory Networks Genes Genetic aspects Genomes Genomics Head & neck cancer Head and neck cancer Head and Neck Neoplasms - mortality Head and Neck Neoplasms - pathology Health aspects Humans Kallikrein Keratin Kinases Lymphatic Metastasis - diagnosis Lymphatic Metastasis - pathology Lymphatic system Medical prognosis Membrane Proteins - metabolism Metastasis Mortality Oncogenes Phenols (Class of compounds) Phospholipases Prognosis Proline Proteins RNA RNA sequencing Studies Survival Analysis Tumor proteins Tumors Variance analysis
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