Fate of Astrocytes in The Gerbil Hippocampus After Transient Global Cerebral Ischemia

Neuronal death and reactive gliosis are major features of brain tissue damage following transient global cerebral ischemia (tgCI). This study investigated long-term changes in neuronal death and astrogliosis in the gerbil hippocampus for 180 days after 5 min of tgCI. A massive loss of pyramidal neur...

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Veröffentlicht in:	International journal of molecular sciences 2019-02, Vol.20 (4), p.845
Hauptverfasser:	Kim, Hyeyoung, Park, Joon Ha, Shin, Myoung Cheol, Cho, Jun Hwi, Lee, Tae-Kyeong, Kim, Hyunjung, Song, Minah, Park, Cheol Woo, Park, Young Eun, Lee, Jae-Chul, Ryoo, Sungwoo, Kim, Young-Myeong, Kim, Dae Won, Hwang, In Koo, Choi, Soo Young, Won, Moo-Ho, Ahn, Ji Hyeon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Apoptosis Astrocytes Astrocytes - metabolism Astrocytes - pathology Blood-brain barrier Caspase-12 Caspase-3 Cell death Cell Lineage Central nervous system Deoxyribonucleic acid DNA DNA fragmentation DNA nucleotidylexotransferase DNA polymerase DNA-directed DNA polymerase Gerbillinae - physiology Glial cells Glial fibrillary acidic protein Glial Fibrillary Acidic Protein - metabolism Glutathione transferase Hippocampus Hippocampus - pathology Ischemia Ischemic Attack, Transient - metabolism Ischemic Attack, Transient - pathology Male Morphology Neurons Neurotransmitters Pyramidal cells Staining and Labeling Vimentin
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