The Relevance of Toxic AGEs (TAGE) Cytotoxicity to NASH Pathogenesis: A Mini-Review

Non-alcoholic fatty liver disease (NAFLD) is currently the most common feature of chronic liver disease. Non-alcoholic steatohepatitis (NASH) is a severe form of NAFLD, and one of its risk factors is hyperglycemia. The chronic ingestion of excessive amounts of high-fructose corn syrup is associated...

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Veröffentlicht in:	Nutrients 2019-02, Vol.11 (2), p.462
Hauptverfasser:	Sakasai-Sakai, Akiko, Takata, Takanobu, Takino, Jun-Ichi, Takeuchi, Masayoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation advanced glycation end products Apoptosis blood serum Cell death Cytotoxicity Diabetes fatty liver Fibrosis Fructose Gene expression Glucose Glucose metabolism glycation glyceraldehyde Hepatitis Hepatocytes high fructose corn syrup Homeostasis Hsc70 protein hyperglycemia Intracellular Leakage liver Liver cancer Liver diseases Metabolism Monocyte chemoattractant protein Monocyte chemoattractant protein 1 Monocytes Mortality Pathogenesis Pathology patients Protein folding Protein transport Proteins Review risk factors Small intestine
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