Connectivity mapping of angiotensin-PPAR interactions involved in the amelioration of non-alcoholic steatohepatitis by Telmisartan

Nonalcoholic fatty liver disease (NAFLD) is a global health problem that is associated with various metabolic disorders. Telmisartan is a potential treatment for NAFLD due to its ability to improve insulin sensitivity and decrease hepatic fat accumulation via modulation of PPARγ, and to suppress hep...

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Veröffentlicht in:	Scientific reports 2019-03, Vol.9 (1), p.4003-4003, Article 4003
Hauptverfasser:	Park, Jung Gyu, Mok, Jong Soo, Han, Young In, Park, Tae Sub, Kang, Keon Wook, Choi, Cheol Soo, Park, Hee Dong, Park, Joonghoon
Format:	Artikel
Sprache:	eng
Schlagworte:	38/39 38/61 631/114/2391 64/60 692/4020/4021/1607/2750 96/95 Angiotensin Angiotensin II Angiotensin II receptors Diabetes Diabetes mellitus Drug therapy Fatty liver Fibrosis Gene expression Global health Humanities and Social Sciences Hypertension Inflammation Insulin Lipids Lipoproteins Liver Liver diseases Metabolic disorders Molecular modelling multidisciplinary NF-κB protein Palmitic acid Peroxisome proliferator-activated receptors RelA protein Science Science (multidisciplinary) Therapeutic applications Transcription
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