Design of novel proliposome formulation for antioxidant peptide, glutathione with enhanced oral bioavailability and stability

To develop proliposome formulations to improve the oral bioavailability of l-glutathione (GSH), GSH-loaded proliposomes were prepared using the granule method. Mannitol was selected as an effective excipient to achieve the desired particle size, entrapment efficiency (EE), and solubility for oral de...

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Veröffentlicht in:Drug delivery 2019-01, Vol.26 (1), p.216-225
Hauptverfasser: Byeon, Jong Chan, Lee, Sang-Eun, Kim, Tae-Hyeon, Ahn, Jung Bin, Kim, Dong-Hyun, Choi, Jin-Seok, Park, Jeong-Sook
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Sprache:eng
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