Contrasting Patterns of Rapid Molecular Evolution within the p53 Network across Mammal and Sauropsid Lineages

Cancer is a threat to multicellular organisms, yet the molecular evolution of pathways that prevent the accumulation of genetic damage has been largely unexplored. The p53 network regulates how cells respond to DNA-damaging stressors. We know little about p53 network molecular evolution as a whole....

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Veröffentlicht in:	Genome biology and evolution 2019-03, Vol.11 (3), p.629-643
Hauptverfasser:	Passow, Courtney N, Bronikowski, Anne M, Blackmon, Heath, Parsai, Shikha, Schwartz, Tonia S, McGaugh, Suzanne E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Evolution, Molecular Genes, p53 Phylogeny Selection, Genetic Vertebrates - genetics
Online-Zugang:	Volltext
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