Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Coq6 Knockout Mice

Although studies have identified >55 genes as causing steroid-resistant nephrotic syndrome (SRNS) and localized its pathogenesis to glomerular podocytes, the disease mechanisms of SRNS remain largely enigmatic. We recently reported that individuals with mutations in COQ6, a coenzyme Q (also calle...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2019-03, Vol.30 (3), p.393-405
Hauptverfasser:	Widmeier, Eugen, Airik, Merlin, Hugo, Hannah, Schapiro, David, Wedel, Johannes, Ghosh, Chandra C, Nakayama, Makiko, Schneider, Ronen, Awad, Agape M, Nag, Anish, Cho, Jang, Schueler, Markus, Clarke, Catherine F, Airik, Rannar, Hildebrandt, Friedhelm
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Research
Online-Zugang:	Volltext
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