Costs and outcomes of Lynch syndrome screening in the Australian colorectal cancer population

Background and Aim Individuals with Lynch syndrome (LS) are at increased risk of LS‐related cancers including colorectal cancer (CRC). CRC tumor screening for mismatch repair (MMR) deficiency is recommended in Australia to identify LS, although its cost‐effectiveness has not been assessed. We aim to...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2018-10, Vol.33 (10), p.1737-1744
Hauptverfasser:	Cenin, Dayna R, Naber, Steffie K, Lansdorp‐Vogelaar, Iris, Jenkins, Mark A, Buchanan, Daniel D, Preen, David B, Ee, Hooi C, O'Leary, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Factors Aged Australia BRAF V600E Brain Neoplasms Clinical Gastroenterology Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Colorectal Neoplasms - etiology Colorectal Neoplasms - genetics Colorectal Neoplasms - prevention & control Colorectal Neoplasms, Hereditary Nonpolyposis - complications Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis Colorectal Neoplasms, Hereditary Nonpolyposis - genetics Colorectal Neoplasms, Hereditary Nonpolyposis - prevention & control Cost-Benefit Analysis Costs cost‐effectiveness Decision Support Techniques Diagnosis DNA Mismatch Repair Female Gastroenterology Humans Immunohistochemistry Lynch syndrome Male Mass Screening - economics Mass Screening - methods Methylation Mismatch repair MLH1 methylation MLH1 protein MutL Protein Homolog 1 Neoplastic Syndromes, Hereditary Probability Proto-Oncogene Proteins B-raf screening Signal Transduction
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