Control freaks-signals and cues governing the regulation of virulence in attaching and effacing pathogens

Enterohaemorrhagic (EHEC) mediates disease using a type 3 secretion system (T3SS), which is encoded on the locus of enterocyte effacement (LEE) and is tightly controlled by master regulators. This system is further modulated by a number of signals that help to fine-tune virulence, including metaboli...

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Veröffentlicht in:	Biochemical Society transactions 2019-02, Vol.47 (1), p.229-238
Hauptverfasser:	Turner, Natasha C A, Connolly, James P R, Roe, Andrew J
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Adhesion Enterocytes - metabolism Enterocytes - microbiology Enterohemorrhagic Escherichia coli - genetics Enterohemorrhagic Escherichia coli - metabolism Enterohemorrhagic Escherichia coli - pathogenicity Epigenesis, Genetic Gene Expression Regulation, Bacterial Review Signal Transduction Transcription, Genetic Virulence
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