Latent Sex Differences in Molecular Signaling That Underlies Excitatory Synaptic Potentiation in the Hippocampus

Excitatory synapses can be potentiated by chemical neuromodulators, including 17β-estradiol (E2), or patterns of synaptic activation, as in long-term potentiation (LTP). Here, we investigated kinases and calcium sources required for acute E2-induced synaptic potentiation in the hippocampus of each s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of neuroscience 2019-02, Vol.39 (9), p.1552-1565
Hauptverfasser:	Jain, Anant, Huang, Guang Zhe, Woolley, Catherine S
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Activation Animals CA1 Region, Hippocampal - metabolism CA1 Region, Hippocampal - physiology Calcium Calcium channels Calcium channels (L-type) Calcium Channels, L-Type - metabolism Calcium ions Calcium-binding protein Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism Calmodulin Cyclic AMP-Dependent Protein Kinases - metabolism Excitatory Postsynaptic Potentials Female Females Gender aspects Gender differences Hippocampus Kinases Long-Term Potentiation Male Males MAP kinase Neuromodulation Organic chemistry Protein kinase A Protein-tyrosine kinase Proteins Pyramidal cells Rats Rats, Sprague-Dawley Rho-associated kinase Sex differences Sex Factors Sex hormones Signaling Synapses Tyrosine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!