Mammary tumor and mastectomy synergistically promote neuroinflammation in a breast cancer survivor model

•Tumor growth and mastectomy alone did not alter inflammatory markers.•Tumor-bearing followed by mastectomy surgery resulted in chronic neuroinflammation.•Responses to immune challenge did not suggest microglial priming.•The inflammation present was likely beneficial rather than maladaptive. Underst...

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Veröffentlicht in:	Brain research 2019-03, Vol.1707, p.133-140
Hauptverfasser:	Emmer, Kathryn M., Walker, William H., Zhang, Ning, DeVries, A. Courtney
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Mastectomy Microglia Neuroinflammation Priming
Online-Zugang:	Volltext
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