Dissociable Disruptions in Thalamic and Hippocampal Resting-State Functional Connectivity in Youth with 22q11.2 Deletions

The 22q11.2 deletion syndrome (22q11DS) is a recurrent copy number variant with high penetrance for developmental neuropsychiatric disorders. Study of individuals with 22q11DS therefore may offer key insights into neural mechanisms underlying such complex illnesses. Resting-state functional connecti...

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Veröffentlicht in:	The Journal of neuroscience 2019-02, Vol.39 (7), p.1301-1319
Hauptverfasser:	Schleifer, Charles, Lin, Amy, Kushan, Leila, Ji, Jie Lisa, Yang, Genevieve, Bearden, Carrie E, Anticevic, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aging - psychology Brain Cerebral cortex Child Circuits Cognitive ability Connectome Copy number Data acquisition DiGeorge Syndrome - diagnostic imaging DiGeorge Syndrome - physiopathology DiGeorge Syndrome - psychology Disorders Disruption Female Functional magnetic resonance imaging Gray Matter - diagnostic imaging Gray Matter - physiopathology Hippocampus Hippocampus - diagnostic imaging Hippocampus - physiopathology Humans Illnesses Magnetic Resonance Imaging Male Medical imaging Mental disorders Nerve Net - diagnostic imaging Nerve Net - physiopathology Neural networks Neural Pathways - diagnostic imaging Neural Pathways - physiopathology Neuroimaging Neurology Permutations Protocol (computers) Schizophrenia Seeds Sensorimotor Cortex - diagnostic imaging Sensorimotor Cortex - physiopathology Substantia grisea Thalamus Thalamus - diagnostic imaging Thalamus - physiopathology Young Adult Youth
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