The effect of metformin therapy on incidence and prognosis in prostate cancer: A systematic review and meta-analysis

The relationship between metformin and prostate cancer (PCa) remains controversial. To clarify this association, the PubMed, Embase and Cochrane library databases were systematically searched from their inception dates to May 23, 2018, using the keywords “metformin” and “prostate cancer” to identify...

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Veröffentlicht in:	Scientific reports 2019-02, Vol.9 (1), p.2218, Article 2218
Hauptverfasser:	He, Kancheng, Hu, Huating, Ye, Senlin, Wang, Haohui, Cui, Rongrong, Yi, Lu
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4025/1752 692/499 Antidiabetics Disease Susceptibility Humanities and Social Sciences Humans Hypoglycemic Agents - adverse effects Hypoglycemic Agents - therapeutic use Incidence Male Medical prognosis Meta-analysis Metformin Metformin - adverse effects Metformin - therapeutic use multidisciplinary Patients Prognosis Proportional Hazards Models Prostate cancer Prostatic Neoplasms - epidemiology Prostatic Neoplasms - etiology Prostatic Neoplasms - mortality Science Science (multidisciplinary) Survival Survival Analysis Systematic review
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