Hyaluronic acid, CD44 and RHAMM regulate myoblast behavior during embryogenesis

Hyaluronic acid (HA) is an extracellular matrix (ECM) component that has been shown to play a significant role in regulating muscle cell behavior during repair and regeneration. For instance, ECM remodeling after muscle injury involves an upregulation in HA expression that is coupled with skeletal m...

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Veröffentlicht in:	Matrix biology 2019-05, Vol.78-79, p.236-254
Hauptverfasser:	Leng, Yue, Abdullah, Ammara, Wendt, Michael K., Calve, Sarah
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD44 CD44 antigen Cell adhesion & migration Cell migration Cell Movement - drug effects Cell proliferation Cell Proliferation - drug effects Cell surface Cells, Cultured Connective tissue Connective Tissue Cells - cytology Connective Tissue Cells - metabolism Connective tissues Embryogenesis Embryonic Development Extracellular matrix Extracellular Matrix Proteins - genetics Extracellular Matrix Proteins - metabolism Female Forelimb - cytology Forelimb - embryology Forelimb - metabolism Gene expression Gene Expression Regulation, Developmental - drug effects Hyaluronan Receptors - genetics Hyaluronan Receptors - metabolism Hyaluronic acid Hyaluronic Acid - metabolism Hymecromone - pharmacology Immunohistochemistry Limb development Male Mice Muscle, Skeletal - embryology Muscle, Skeletal - metabolism Musculoskeletal system Myoblasts Myoblasts - cytology Myoblasts - drug effects Myoblasts - metabolism Myogenesis RHAMM Ribonucleic acid RNA Skeletal muscle Spatial distribution Stem cells
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