Initial experience with precipitating hydrophobic injectable liquid in cerebral arteriovenous malformations
Background Precipitating hydrophobic injectable liquid is a newly introduced liquid embolic agent for endovascular embolization with some technical advantages over other liquid embolic agents. We present our initial experience with precipitating hydrophobic injectable liquid in the endovascular trea...
Gespeichert in:
| Veröffentlicht in: | Interventional neuroradiology 2019-02, Vol.25 (1), p.58-65 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 65 |
|---|---|
| container_issue | 1 |
| container_start_page | 58 |
| container_title | Interventional neuroradiology |
| container_volume | 25 |
| creator | Sirakov, Stanimir S Sirakov, Alexander Minkin, Krasimir Hristov, Hristo Ninov, Kristian Penkov, Marin Karakostov, Vasil Orlov, Kirill Gorbatykh, Anton Kislitsin, Dmitry Raychev, Radoslav |
| description | Background
Precipitating hydrophobic injectable liquid is a newly introduced liquid embolic agent for endovascular embolization with some technical advantages over other liquid embolic agents. We present our initial experience with precipitating hydrophobic injectable liquid in the endovascular treatment of cerebral arteriovenous malformations.
Methods
From October 2015 to January 2018, 27 patients harboring cerebral arteriovenous malformations underwent endovascular embolization with precipitating hydrophobic injectable liquid 25. Clinical features, angiographic results, procedural details, complications, and follow-up details were retrospectively analyzed.
Results
Twenty-seven patients with cerebral arteriovenous malformations were included. Total obliteration in one endovascular session was confirmed for 14/27 (52%) patients. Partial embolization was attained in 13 patients (48%) in whom staged treatment with following radiosurgery or surgery was planned. No mortality was recorded in this series. Complications during or after the embolization occurred in six of 27 (22.2%) patients.
Conclusion
In our initial experience, precipitating hydrophobic injectable liquid has acceptable clinical outcome comparable to other liquid embolic agents. Although this is the largest reported study in arteriovenous malformation treatment with precipitating hydrophobic injectable liquid, further studies are needed to validate its safety and efficacy. |
| doi_str_mv | 10.1177/1591019918798808 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6378517</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1591019918798808</sage_id><sourcerecordid>2109332707</sourcerecordid><originalsourceid>FETCH-LOGICAL-c434t-c51dc64f07d60ca25f669ff4fc17652a35c3a66329dbc369bf0153523168d9233</originalsourceid><addsrcrecordid>eNp1kc1v1DAQxS0EotvCnRPKkUvAY6-d-IKEKj4qVeICZ8txxrteEju1nUL_e7zatgIkTiP5vfnNjB8hr4C-Bei6dyAUUFAK-k71Pe2fkA3jvWgZBXhKNke5Pepn5DznA6VScAXPyRmnjHHZyw35cRV88WZq8NeCyWOw2Pz0Zd8sCa1ffDHFh12zvxtTXPZx8Lbx4YC2mGHCZvI3qx_rS2Mx4ZAqx6RSOfEWQ1xzM5vJxTRXSAz5BXnmzJTx5X29IN8_ffx2-aW9_vr56vLDdWu3fFtaK2C0cutoN0pqDRNOSuXc1lnopGCGC8uNlJypcbBcqsFREFwwDrIfFeP8grw_cZd1mHG0GErdTC_Jzybd6Wi8_lsJfq938VZL3vUCugp4cw9I8WbFXPTss8VpMgHrVZoBVZyzjh6t9GS1Keac0D2OAaqPGel_M6otr_9c77HhIZRqaE-GbHaoD3FNoX7X_4G_AfhFnMs</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2109332707</pqid></control><display><type>article</type><title>Initial experience with precipitating hydrophobic injectable liquid in cerebral arteriovenous malformations</title><source>SAGE Complete A-Z List</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Sirakov, Stanimir S ; Sirakov, Alexander ; Minkin, Krasimir ; Hristov, Hristo ; Ninov, Kristian ; Penkov, Marin ; Karakostov, Vasil ; Orlov, Kirill ; Gorbatykh, Anton ; Kislitsin, Dmitry ; Raychev, Radoslav</creator><creatorcontrib>Sirakov, Stanimir S ; Sirakov, Alexander ; Minkin, Krasimir ; Hristov, Hristo ; Ninov, Kristian ; Penkov, Marin ; Karakostov, Vasil ; Orlov, Kirill ; Gorbatykh, Anton ; Kislitsin, Dmitry ; Raychev, Radoslav</creatorcontrib><description>Background
Precipitating hydrophobic injectable liquid is a newly introduced liquid embolic agent for endovascular embolization with some technical advantages over other liquid embolic agents. We present our initial experience with precipitating hydrophobic injectable liquid in the endovascular treatment of cerebral arteriovenous malformations.
Methods
From October 2015 to January 2018, 27 patients harboring cerebral arteriovenous malformations underwent endovascular embolization with precipitating hydrophobic injectable liquid 25. Clinical features, angiographic results, procedural details, complications, and follow-up details were retrospectively analyzed.
Results
Twenty-seven patients with cerebral arteriovenous malformations were included. Total obliteration in one endovascular session was confirmed for 14/27 (52%) patients. Partial embolization was attained in 13 patients (48%) in whom staged treatment with following radiosurgery or surgery was planned. No mortality was recorded in this series. Complications during or after the embolization occurred in six of 27 (22.2%) patients.
Conclusion
In our initial experience, precipitating hydrophobic injectable liquid has acceptable clinical outcome comparable to other liquid embolic agents. Although this is the largest reported study in arteriovenous malformation treatment with precipitating hydrophobic injectable liquid, further studies are needed to validate its safety and efficacy.</description><identifier>ISSN: 1591-0199</identifier><identifier>EISSN: 2385-2011</identifier><identifier>DOI: 10.1177/1591019918798808</identifier><identifier>PMID: 30223686</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adolescent ; Adult ; Angiography, Digital Subtraction ; AV Shunts ; Cerebral Angiography ; Child ; Dimethyl Sulfoxide - administration & dosage ; Embolization, Therapeutic - methods ; Female ; Humans ; Intracranial Arteriovenous Malformations - diagnostic imaging ; Intracranial Arteriovenous Malformations - therapy ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome</subject><ispartof>Interventional neuroradiology, 2019-02, Vol.25 (1), p.58-65</ispartof><rights>The Author(s) 2018</rights><rights>The Author(s) 2018 2018 SAGE Publications</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c434t-c51dc64f07d60ca25f669ff4fc17652a35c3a66329dbc369bf0153523168d9233</citedby><cites>FETCH-LOGICAL-c434t-c51dc64f07d60ca25f669ff4fc17652a35c3a66329dbc369bf0153523168d9233</cites><orcidid>0000-0002-7721-7449</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378517/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378517/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,21800,27903,27904,43599,43600,53768,53770</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30223686$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sirakov, Stanimir S</creatorcontrib><creatorcontrib>Sirakov, Alexander</creatorcontrib><creatorcontrib>Minkin, Krasimir</creatorcontrib><creatorcontrib>Hristov, Hristo</creatorcontrib><creatorcontrib>Ninov, Kristian</creatorcontrib><creatorcontrib>Penkov, Marin</creatorcontrib><creatorcontrib>Karakostov, Vasil</creatorcontrib><creatorcontrib>Orlov, Kirill</creatorcontrib><creatorcontrib>Gorbatykh, Anton</creatorcontrib><creatorcontrib>Kislitsin, Dmitry</creatorcontrib><creatorcontrib>Raychev, Radoslav</creatorcontrib><title>Initial experience with precipitating hydrophobic injectable liquid in cerebral arteriovenous malformations</title><title>Interventional neuroradiology</title><addtitle>Interv Neuroradiol</addtitle><description>Background
Precipitating hydrophobic injectable liquid is a newly introduced liquid embolic agent for endovascular embolization with some technical advantages over other liquid embolic agents. We present our initial experience with precipitating hydrophobic injectable liquid in the endovascular treatment of cerebral arteriovenous malformations.
Methods
From October 2015 to January 2018, 27 patients harboring cerebral arteriovenous malformations underwent endovascular embolization with precipitating hydrophobic injectable liquid 25. Clinical features, angiographic results, procedural details, complications, and follow-up details were retrospectively analyzed.
Results
Twenty-seven patients with cerebral arteriovenous malformations were included. Total obliteration in one endovascular session was confirmed for 14/27 (52%) patients. Partial embolization was attained in 13 patients (48%) in whom staged treatment with following radiosurgery or surgery was planned. No mortality was recorded in this series. Complications during or after the embolization occurred in six of 27 (22.2%) patients.
Conclusion
In our initial experience, precipitating hydrophobic injectable liquid has acceptable clinical outcome comparable to other liquid embolic agents. Although this is the largest reported study in arteriovenous malformation treatment with precipitating hydrophobic injectable liquid, further studies are needed to validate its safety and efficacy.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Angiography, Digital Subtraction</subject><subject>AV Shunts</subject><subject>Cerebral Angiography</subject><subject>Child</subject><subject>Dimethyl Sulfoxide - administration & dosage</subject><subject>Embolization, Therapeutic - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Intracranial Arteriovenous Malformations - diagnostic imaging</subject><subject>Intracranial Arteriovenous Malformations - therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><issn>1591-0199</issn><issn>2385-2011</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1v1DAQxS0EotvCnRPKkUvAY6-d-IKEKj4qVeICZ8txxrteEju1nUL_e7zatgIkTiP5vfnNjB8hr4C-Bei6dyAUUFAK-k71Pe2fkA3jvWgZBXhKNke5Pepn5DznA6VScAXPyRmnjHHZyw35cRV88WZq8NeCyWOw2Pz0Zd8sCa1ffDHFh12zvxtTXPZx8Lbx4YC2mGHCZvI3qx_rS2Mx4ZAqx6RSOfEWQ1xzM5vJxTRXSAz5BXnmzJTx5X29IN8_ffx2-aW9_vr56vLDdWu3fFtaK2C0cutoN0pqDRNOSuXc1lnopGCGC8uNlJypcbBcqsFREFwwDrIfFeP8grw_cZd1mHG0GErdTC_Jzybd6Wi8_lsJfq938VZL3vUCugp4cw9I8WbFXPTss8VpMgHrVZoBVZyzjh6t9GS1Keac0D2OAaqPGel_M6otr_9c77HhIZRqaE-GbHaoD3FNoX7X_4G_AfhFnMs</recordid><startdate>20190201</startdate><enddate>20190201</enddate><creator>Sirakov, Stanimir S</creator><creator>Sirakov, Alexander</creator><creator>Minkin, Krasimir</creator><creator>Hristov, Hristo</creator><creator>Ninov, Kristian</creator><creator>Penkov, Marin</creator><creator>Karakostov, Vasil</creator><creator>Orlov, Kirill</creator><creator>Gorbatykh, Anton</creator><creator>Kislitsin, Dmitry</creator><creator>Raychev, Radoslav</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7721-7449</orcidid></search><sort><creationdate>20190201</creationdate><title>Initial experience with precipitating hydrophobic injectable liquid in cerebral arteriovenous malformations</title><author>Sirakov, Stanimir S ; Sirakov, Alexander ; Minkin, Krasimir ; Hristov, Hristo ; Ninov, Kristian ; Penkov, Marin ; Karakostov, Vasil ; Orlov, Kirill ; Gorbatykh, Anton ; Kislitsin, Dmitry ; Raychev, Radoslav</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c434t-c51dc64f07d60ca25f669ff4fc17652a35c3a66329dbc369bf0153523168d9233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Angiography, Digital Subtraction</topic><topic>AV Shunts</topic><topic>Cerebral Angiography</topic><topic>Child</topic><topic>Dimethyl Sulfoxide - administration & dosage</topic><topic>Embolization, Therapeutic - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Intracranial Arteriovenous Malformations - diagnostic imaging</topic><topic>Intracranial Arteriovenous Malformations - therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sirakov, Stanimir S</creatorcontrib><creatorcontrib>Sirakov, Alexander</creatorcontrib><creatorcontrib>Minkin, Krasimir</creatorcontrib><creatorcontrib>Hristov, Hristo</creatorcontrib><creatorcontrib>Ninov, Kristian</creatorcontrib><creatorcontrib>Penkov, Marin</creatorcontrib><creatorcontrib>Karakostov, Vasil</creatorcontrib><creatorcontrib>Orlov, Kirill</creatorcontrib><creatorcontrib>Gorbatykh, Anton</creatorcontrib><creatorcontrib>Kislitsin, Dmitry</creatorcontrib><creatorcontrib>Raychev, Radoslav</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Interventional neuroradiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sirakov, Stanimir S</au><au>Sirakov, Alexander</au><au>Minkin, Krasimir</au><au>Hristov, Hristo</au><au>Ninov, Kristian</au><au>Penkov, Marin</au><au>Karakostov, Vasil</au><au>Orlov, Kirill</au><au>Gorbatykh, Anton</au><au>Kislitsin, Dmitry</au><au>Raychev, Radoslav</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Initial experience with precipitating hydrophobic injectable liquid in cerebral arteriovenous malformations</atitle><jtitle>Interventional neuroradiology</jtitle><addtitle>Interv Neuroradiol</addtitle><date>2019-02-01</date><risdate>2019</risdate><volume>25</volume><issue>1</issue><spage>58</spage><epage>65</epage><pages>58-65</pages><issn>1591-0199</issn><eissn>2385-2011</eissn><abstract>Background
Precipitating hydrophobic injectable liquid is a newly introduced liquid embolic agent for endovascular embolization with some technical advantages over other liquid embolic agents. We present our initial experience with precipitating hydrophobic injectable liquid in the endovascular treatment of cerebral arteriovenous malformations.
Methods
From October 2015 to January 2018, 27 patients harboring cerebral arteriovenous malformations underwent endovascular embolization with precipitating hydrophobic injectable liquid 25. Clinical features, angiographic results, procedural details, complications, and follow-up details were retrospectively analyzed.
Results
Twenty-seven patients with cerebral arteriovenous malformations were included. Total obliteration in one endovascular session was confirmed for 14/27 (52%) patients. Partial embolization was attained in 13 patients (48%) in whom staged treatment with following radiosurgery or surgery was planned. No mortality was recorded in this series. Complications during or after the embolization occurred in six of 27 (22.2%) patients.
Conclusion
In our initial experience, precipitating hydrophobic injectable liquid has acceptable clinical outcome comparable to other liquid embolic agents. Although this is the largest reported study in arteriovenous malformation treatment with precipitating hydrophobic injectable liquid, further studies are needed to validate its safety and efficacy.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>30223686</pmid><doi>10.1177/1591019918798808</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-7721-7449</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1591-0199 |
| ispartof | Interventional neuroradiology, 2019-02, Vol.25 (1), p.58-65 |
| issn | 1591-0199 2385-2011 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6378517 |
| source | SAGE Complete A-Z List; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Adolescent Adult Angiography, Digital Subtraction AV Shunts Cerebral Angiography Child Dimethyl Sulfoxide - administration & dosage Embolization, Therapeutic - methods Female Humans Intracranial Arteriovenous Malformations - diagnostic imaging Intracranial Arteriovenous Malformations - therapy Male Middle Aged Retrospective Studies Treatment Outcome |
| title | Initial experience with precipitating hydrophobic injectable liquid in cerebral arteriovenous malformations |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T09%3A53%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Initial%20experience%20with%20precipitating%20hydrophobic%20injectable%20liquid%20in%20cerebral%20arteriovenous%20malformations&rft.jtitle=Interventional%20neuroradiology&rft.au=Sirakov,%20Stanimir%20S&rft.date=2019-02-01&rft.volume=25&rft.issue=1&rft.spage=58&rft.epage=65&rft.pages=58-65&rft.issn=1591-0199&rft.eissn=2385-2011&rft_id=info:doi/10.1177/1591019918798808&rft_dat=%3Cproquest_pubme%3E2109332707%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2109332707&rft_id=info:pmid/30223686&rft_sage_id=10.1177_1591019918798808&rfr_iscdi=true |