Impact of HIV-ART on the restoration of Th17 and Treg cells in blood and female genital mucosa

The aim of this study was to evaluate the effectiveness of antiretroviral treatment (ART) on the proportion and functions of Th17 and Treg cells in peripheral blood and female genital tract (FGT) respectively. To this aim, samples from 41 HIV-neg, 33 HIV+ ART-naïve and 32 HIV+ ART+ subjects were obt...

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Veröffentlicht in:	Scientific reports 2019-02, Vol.9 (1), p.1978, Article 1978
Hauptverfasser:	Caruso, María Paula, Falivene, Juliana, Holgado, María Pía, Zurita, Diego Hernán, Laufer, Natalia, Castro, Carina, Nico, Ángeles, Maeto, Cynthia, Salido, Jimena, Pérez, Héctor, Salomón, Horacio, Cahn, Pedro, Sued, Omar, Fink, Valeria, Turk, Gabriela, Gherardi, María Magdalena
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/21 13/31 631/250/255/2514 631/250/347 631/326/596/2553 82/80 Adult Anti-Retroviral Agents - pharmacology Antiretroviral agents Antiretroviral drugs Antiretroviral therapy CCL17 protein CCL20 protein Chemokine CCL17 - analysis Chemokine CCL20 - analysis Chemokine CXCL1 - analysis Chemokine CXCL5 - analysis Chemokines Cytokines - analysis Female Females Genital tract Genitalia, Female - cytology Genitalia, Female - drug effects Genitalia, Female - immunology Helper cells HIV HIV Infections - drug therapy Human immunodeficiency virus Humanities and Social Sciences Humans Immunoregulation Interleukin 21 Interleukin-17 - analysis Intestine Leukocytes (mononuclear) Lymphocytes T Middle Aged Mucosa Mucous Membrane - cytology Mucous Membrane - immunology Mucous Membrane - metabolism multidisciplinary Peripheral blood Science Science (multidisciplinary) T-Lymphocytes, Regulatory - drug effects T-Lymphocytes, Regulatory - immunology Th17 Cells - drug effects Th17 Cells - immunology
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