Ghrelin Receptor Influence on Cocaine Reward is Not Directly Dependent on Peripheral Acyl-Ghrelin

The peptide hormone acyl-ghrelin and its receptor, GHSR 1a , represent intriguing therapeutic targets due to their actions in metabolic homeostasis and reward activity. However, this pleotropic activity makes it difficult to intervene in this system without inducing unwanted effects. Thus, it is des...

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Veröffentlicht in:	Scientific reports 2019-02, Vol.9 (1), p.1841-1841, Article 1841
Hauptverfasser:	Wenthur, Cody J., Gautam, Ritika, Zhou, Bin, Vendruscolo, Leandro F., Leggio, Lorenzo, Janda, Kim D.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 631/378/1788 631/92/436/2387 64/60 692/163/2743 Animals Appetite - physiology Blood-Brain Barrier Central Nervous System - physiology Cocaine Cocaine - metabolism Craving Energy Metabolism Energy storage Ghrelin Ghrelin - analogs & derivatives Ghrelin - metabolism Homeostasis Humanities and Social Sciences Humans Male Mice multidisciplinary Receptors, Ghrelin - immunology Receptors, Ghrelin - metabolism Reinforcement Reward Science Science (multidisciplinary) Signal Transduction Therapeutic applications Weight Gain
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