Pharmacogenetics of Chemotherapy-Induced Cardiotoxicity

Purpose of Review The goal of this review is to summarize current understanding of pharmacogenetics and pharmacogenomics in chemotherapy-induced cardiotoxicity. Recent Findings Most of the studies rely on in vitro cytotoxic assays. There have been several smaller scale candidate gene approaches and...

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Veröffentlicht in:	Current oncology reports 2018-07, Vol.20 (7), p.52-8, Article 52
Hauptverfasser:	Chang, Vivian Y., Wang, Jessica J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Cancer Cardio-oncology (EH Yang Cardiotoxicity Cardiotoxicity - etiology Cardiotoxicity - genetics Chemotherapy Children Cytotoxicity Daunorubicin Daunorubicin - adverse effects Daunorubicin - pharmacology Doxorubicin Doxorubicin - adverse effects Doxorubicin - pharmacology Genetic diversity Genetic Testing Genomes Humans Life span Medicine Medicine & Public Health Mice Oncology Pharmacogenetics Pharmacogenetics - methods Pharmacogenomics Polymorphism, Single Nucleotide Quality of life Receptors, Retinoic Acid - genetics Retinoic Acid Receptor gamma Section Editor Topical Collection on Cardio-oncology
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