The curcumin analog EF24 is a novel senolytic agent

Cellular senescence is a hallmark of aging because senescent cells (SCs) accumulate with aging and play a causative role in age-related diseases. Selectively eliminating SCs has been emerging as a new strategy for treating age-related diseases and extending healthspan. Curcumin and its analogs have...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2019-01, Vol.11 (2), p.771-782
Hauptverfasser:	Li, Wen, He, Yonghan, Zhang, Rongping, Zheng, Guangrong, Zhou, Daohong
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzylidene Compounds - pharmacology Cell Line Cell Survival Cellular Senescence - drug effects Epithelial Cells - drug effects Fibroblasts - drug effects Humans Piperidones - pharmacology Reactive Oxygen Species Research Paper
Online-Zugang:	Volltext
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