Toxicity and Patient-Reported Outcomes of a Phase 2 Randomized Trial of Prostate and Pelvic Lymph Node Versus Prostate only Radiotherapy in Advanced Localised Prostate Cancer (PIVOTAL)

To establish the toxicity profile of high-dose pelvic lymph node intensity-modulated radiation therapy (IMRT) and to assess whether it is safely deliverable at multiple centers. In this phase 2 noncomparative multicenter trial, 124 patients with locally advanced, high-risk prostate cancer were rando...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2019-03, Vol.103 (3), p.605-617
Hauptverfasser:	Dearnaley, David, Griffin, Clare L., Lewis, Rebecca, Mayles, Philip, Mayles, Helen, Naismith, Olivia F., Harris, Victoria, Scrase, Christopher D., Staffurth, John, Syndikus, Isabel, Zarkar, Anjali, Ford, Daniel R., Rimmer, Yvonne L., Horan, Gail, Khoo, Vincent, Frew, John, Venkitaraman, Ramachandran, Hall, Emma
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biopsy Humans Lymph Nodes - drug effects Lymphatic Irradiation - methods Lymphatic Metastasis Male Middle Aged Patient Reported Outcome Measures Pelvis - radiation effects Prostate - radiation effects Prostatic Neoplasms - radiotherapy Radiotherapy Dosage Radiotherapy, Intensity-Modulated - methods Treatment Outcome
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