Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers

Epithelial cells and differentiated fiber cells represent distinct compartments in the ocular lens. While previous studies have revealed proteins that are preferentially expressed in epithelial vs. fiber cells, a comprehensive proteomics library comparing the molecular compositions of epithelial vs....

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Veröffentlicht in:	Experimental eye research 2019-02, Vol.179, p.32-46
Hauptverfasser:	Zhao, Yilin, Wilmarth, Phillip A., Cheng, Catherine, Limi, Saima, Fowler, Velia M., Zheng, Deyou, David, Larry L., Cvekl, Ales
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Cell Differentiation - physiology Chromatography, Liquid Crystallins - metabolism Differentiation Epithelial Cells - metabolism Fluorescent Antibody Technique, Indirect Gene Expression - physiology Gene Expression Profiling Lens Lens, Crystalline - cytology Lens, Crystalline - metabolism Mass spectrometry Mice Proteome Proteome - physiology Proteomics RNA, Messenger - genetics RNA-Seq Tandem Mass Spectrometry Transcription factors Transcription Factors - metabolism Transcriptome Transcriptome - physiology
Online-Zugang:	Volltext
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