Polymorphisms in RAS/RAF/MEK/ERK Pathway Are Associated with Gastric Cancer

The RAS/RAF/MEK/ERK pathway regulates certain cellular functions, including cell proliferation, differentiation, survival, and apoptosis. Dysregulation of this pathway leads to the occurrence and progression of cancers mainly by somatic mutations. This study aimed to assess if polymorphisms of the R...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genes 2018-12, Vol.10 (1), p.20
Hauptverfasser:	Gonzalez-Hormazabal, Patricio, Musleh, Maher, Bustamante, Marco, Stambuk, Juan, Pisano, Raul, Valladares, Hector, Lanzarini, Enrique, Chiong, Hector, Rojas, Jorge, Suazo, Jose, Castro, V Gonzalo, Jara, Lilian, Berger, Zoltan
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Binding sites Cell differentiation Cell proliferation Cell survival Extracellular signal-regulated kinase Gastric cancer Gene expression Genetic engineering Genomes Genomics Genotype & phenotype Hospitals Kinases Medical research Metabolic pathways Mutation Phosphorylation Population Principal components analysis Proteins Public health Raf protein Single-nucleotide polymorphism Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!