Genome-wide DNA methylation comparison between live human brain and peripheral tissues within individuals

Differential DNA methylation in the brain is associated with many psychiatric diseases, but access to brain tissues is essentially limited to postmortem samples. The use of surrogate tissues has become common in identifying methylation changes associated with psychiatric disease. In this study, we d...

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Veröffentlicht in:	Translational psychiatry 2019-01, Vol.9 (1), p.47, Article 47
Hauptverfasser:	Braun, Patricia R., Han, Shizhong, Hing, Benjamin, Nagahama, Yasunori, Gaul, Lindsey N., Heinzman, Jonathan T., Grossbach, Andrew J., Close, Liesl, Dlouhy, Brian J., Howard, Matthew A., Kawasaki, Hiroto, Potash, James B., Shinozaki, Gen
Format:	Artikel
Sprache:	eng
Schlagworte:	45/22 45/61 631/208/212 631/378/2584 96/31 Adolescent Adult Behavioral Sciences Biological Psychology Brain - metabolism Child Child, Preschool CpG Islands Deoxyribonucleic acid DNA DNA Methylation Epigenesis, Genetic Female Genome-Wide Association Study Genomes Humans Male Medicine Medicine & Public Health Mental Disorders - genetics Middle Aged Neurosciences Pharmacotherapy Psychiatry Saliva - metabolism Young Adult
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