Dietary epicatechin improves survival and delays skeletal muscle degeneration in aged mice

ABSTRACT We recently reported that epicatechin, a bioactive compound that occurs naturally in various common foods, promoted general health and survival of obese diabetic mice. It remains to be determined whether epicatechin extends health span and delays the process of aging. In the present study,...

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Veröffentlicht in:	The FASEB journal 2019-01, Vol.33 (1), p.965-977
Hauptverfasser:	Si, Hongwei, Wang, Xiaoyong, Zhang, Longyun, Parnell, Laurence D., Ahmed, Bulbul, LeRoith, Tanya, Ansah, Twum-Ampofo, Zhang, Lijuan, Li, Jianwei, Ordovás, José M., Si, Hongzong, Liu, Dongmin, Lai, Chao-Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animals antiaging Catechin - administration & dosage Diabetes Mellitus, Experimental - metabolism Diet extracellular matrix pathway lifespan Male Metabolomics Mice Mice, Inbred C57BL Muscle, Skeletal - metabolism Muscle, Skeletal - pathology Muscular Atrophy - metabolism NAD - metabolism nicotinamide pathway Peroxisome Proliferator-Activated Receptors - metabolism PPAR pathway Survival Rate
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